Virtual Biopsy by Electrical Impedance Spectroscopy in Barrett's Carcinoma.

ABSTRACT:

Purpose

Early detection of adenocarcinomas in the esophagus is crucial for achieving curative endoscopic therapy. Targeted biopsies of suspicious lesions, as well as four-quadrant biopsies, represent the current diagnostic standard. However, this procedure is time-consuming, cost-intensive, and examiner-dependent. The aim of this study was to test whether impedance spectroscopy is capable of distinguishing between healthy, premalignant, and malignant lesions. An ex vivo measurement method was developed to examine esophageal lesions using impedance spectroscopy immediately after endoscopic resection.

Methods

After endoscopic resection of suspicious lesions in the esophagus, impedance measurements were performed on resected cork-covered tissue using a measuring head that was d

SUBMITTER: Bloßer S 

PROVIDER: S-EPMC9630236 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature