Sex-related differences in violence exposure, neural reactivity to threat, and mental health.

ABSTRACT: The prefrontal cortex (PFC), hippocampus, and amygdala play an important role in emotional health. However, adverse life events (e.g., violence exposure) affect the function of these brain regions, which may lead to disorders such as depression and anxiety. Depression and anxiety disproportionately affect women compared to men, and this disparity may reflect sex differences in the neural processes that underlie emotion expression and regulation. The present study investigated sex differences in the relationship between violence exposure and the neural processes that underlie emotion regulation. In the present study, 200 participants completed a Pavlovian fear conditioning procedure in which cued and non-cued threats (i.e., unconditioned stimuli) were presented during functional magnetic re

SUBMITTER: Dark HE 

PROVIDER: S-EPMC9630543 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature