Genetic characterization of dengue virus from patients presenting multi-serotypic infections in the Northern West Bengal, India.

ABSTRACT: Northern West Bengal, popularly known as North Bengal, is a dengue-endemic area, which has been severely affected by Dengue in the past few years resulting in massive hospitalizations and deaths. Genetic characterization of the circulating endemic dengue virus (DENV) serotypes is of paramount importance for the epidemiological understanding of the infection and subsequent vaccine development. The present study was conceived to characterize circulating dengue serotypes and to undertake phylogenetic study. EDTA blood samples of all (N = 83) NS1-positive cases of patients with acute febrile illness referred to different health care facilities were collected and processed for RNA isolation followed by the complementary DNA (cDNA) preparation. Serotype determination of dengue infection was done

SUBMITTER: Roy SK 

PROVIDER: S-EPMC9630820 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature