Association of Taxane Type With Patient-Reported Chemotherapy-Induced Peripheral Neuropathy Among Patients With Breast Cancer.

ABSTRACT:

Importance

Understanding the detailed symptom spectrum of chemotherapy-induced peripheral neuropathy (CIPN) could facilitate shared decision-making and promote early intervention.

Objective

To compare the symptom spectrum of patient-reported CIPN associated with nab-paclitaxel, paclitaxel, and docetaxel treatments among patients with breast cancer.

Design, setting, and participants

This prospective cohort study was conducted at 9 medical centers across China from 2019 to 2021. Participants included hospitalized women diagnosed with invasive breast cancer, assessed with overlap propensity score weighting. Data were analyzed from from December 2021 to May 2022.

Exposures

Treatment with nab-paclitaxel-, paclitaxel-, or docetaxel-based regimens.

Main outcomes an

SUBMITTER: Mo H 

PROVIDER: S-EPMC9631104 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature