Early intubation and clinical outcomes in patients with severe COVID-19: a systematic review and meta-analysis.

ABSTRACT:

Background

Evidence regarding the timing of the application of mechanical ventilation among patients with severe coronavirus disease (COVID-19) is insufficient. This systematic review and meta-analysis aimed to evaluate the effectiveness of early intubation compared to late intubation in patients with severe and critical COVID-19.

Methods

For this study, we searched the MEDLINE, EMBASE, and Cochrane databases as well as one Korean domestic database on July 15, 2021. We updated the search monthly from September 10, 2021 to February 10, 2022. Studies that compared early intubation with late intubation in patients with severe COVID-19 were eligible for inclusion. Relative risk (RR) and mean difference (MD) were calculated as measures of effect using the random-effects model for

SUBMITTER: Lee HJ 

PROVIDER: S-EPMC9631590 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature