Pyrazoline Containing Compounds as Therapeutic Targets for Neurodegenerative Disorders.

ABSTRACT: Pyrazolines are a significant class of heterocyclic compounds with essential biological activities. They are quite stable, which has inspired medicinal chemists to experiment with the ring's structure in many different ways to create a variety of pharmacological activities. The structures of numerous commercially available therapeutic agents contain a pyrazoline ring. Pyrazolines are well-known for their ability to treat neurodegenerative diseases. The neurodegenerative diseases that affect huge populations globally include Alzheimer's disease (AD), Parkinson's disease (PD), and psychiatric disorders. The neuroprotective properties of pyrazolines published since 2003 are covered in the current review. Structure-activity relationships (SARs), molecular docking simulation, anticholinesterase

SUBMITTER: Ahsan MJ 

PROVIDER: S-EPMC9631758 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature