Fecal microbiota transplantation in patients with post-infectious irritable bowel syndrome: A randomized, clinical trial.

ABSTRACT:

Introduction

Research in recent years has shown the potential benefits of fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS). Acute infectious gastroenteritis is a well-established risk factor for developing such forms of IBS as post-infectious IBS (PI-IBS). However, the effective use of FMT in patients with IP-IBS has not yet been clarified.

Aim

The study aimed to conduct a single-center, randomized clinical trial (RCT) to assess FMT's safety, clinical and microbiological efficacy in patients with PI-IBS.

Materials and methods

Patients with PI-IBS were randomized into two groups: I (standard-care, n = 29) were prescribed basic therapy, namely a low FODMAP diet, as well as Otilonium Bromide (1 tablet TID) and a multi-strain probiotic (1 c

SUBMITTER: Tkach S 

PROVIDER: S-EPMC9631772 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature