A randomized controlled trial to evaluate the effectiveness of a novel mouth rinse in patients with gingivitis.

ABSTRACT:

Background

This single-center, randomized controlled trial aimed to determine the effectiveness of a novel, biofilm-disrupting, mouth rinse that combines Cetylpyridinium chloride (CPC) and essential oils in preventing re-accumulation of supragingival plaque and supragingival microbiome in patients with gingivitis after dental prophylaxis.

Methods

One hundred eighteen participants were randomly assigned in a 1:1 ratio to receive twice-daily test mouth rinse (59) or carrier rinse control (59) for 12 weeks after dental prophylaxis.

Results

In a per-protocol analysis that included patients who completed the intervention, the treatment group (39) had significantly lower supragingival plaque scores at 6 and 12 weeks compared to the control group (41; p = 0.022). Both groups

SUBMITTER: Newman BA 

PROVIDER: S-EPMC9632080 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature