Availability of Results of Trials Studying Pancreatic Adenocarcinoma over the Past 10 Years.

ABSTRACT:

Background

Pancreatic adenocarcinoma (PDAC) is a lethal cancer with few therapeutic options. Availability of results is a crucial step in interventional research. Our aim was to evaluate results availability for trials in patients with PDAC and explore associated factors.

Materials and methods

We performed a retrospective cohort study and searched the ClinicalTrials.gov registry for trials evaluating PDAC management with a primary completion date between 1 January 2010 and 1 June 2020. Then, we searched for results submitted on ClinicalTrials.gov and/or published. Our primary outcome was the proportion of PDAC trials with available results: submitted on ClinicalTrials.gov (either publicly available or undergoing quality control check) and/or published in a full-text article.

SUBMITTER: Pellat A 

PROVIDER: S-EPMC9632316 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature