Association Between Geriatric Assessment and Post-Chemotherapy Functional Status in Older Patients with Cancer.

ABSTRACT:

Background

Maintaining functional status is among the most important patient-centered outcomes for older adults with cancer. This study investigated the association between comprehensive geriatric assessment (CGA) and progressive disease or decline of IADL-independence 1 year after chemotherapy, overall survival (OS), and premature termination of chemotherapy. CGA-based functional status and quality of life (QOL) 1 year after chemotherapy are also described.

Methods

This prospective cohort study involved patients aged ≥65 years treated with chemotherapy for any cancer type. CGA and the G8-screening tool were performed before and after the completion of chemotherapy. Analyses were adjusted for tumor type and treatment intent: (a) indolent hematological malignancies, (b) aggre

SUBMITTER: Rier HN 

PROVIDER: S-EPMC9632320 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature