Systematic review and meta-analysis of oral squamous cell carcinoma associated oral microbiome.

ABSTRACT: The intersection between the human oral microbiome and oral health is an emerging area of study which has gained momentum over the last decade. This momentum has motivated a search for associations between the oral microbiome and oral cancer, in hopes of identifying possible biomarkers that facilitate earlier diagnosis and improved prognosis for patients with that disease. The present study examined the relationship between the microbiome in the human oral cavity and oral squamous cell carcinoma (OSCC). We searched the literature for case-control studies which focused on the relationship between the human oral microbiome and OSCC. We aggregated three types of data from these studies: bacteriome data at the genus level, predicted functional pathway data, and gene abundance data. From these

SUBMITTER: Peter TK 

PROVIDER: S-EPMC9632422 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature