Anticholinergic Drug Burden and Neurocognitive Performance in the Study of Latinos-Investigation of Neurocognitive Aging.

ABSTRACT:

Background

Studies of cumulative anticholinergic drug burden on cognitive function and impairment are emerging, yet few for Hispanics/Latinos.

Objective

To examine associations between anticholinergic use and neurocognitive performance outcomes among diverse Hispanics/Latinos.

Methods

This prospective cohort study included diverse Hispanic/Latino participants, enrolled in the Study of Latinos-Investigation of Neurocognitive, from New York, Chicago, Miami, and San Diego (n = 6,249). Survey linear regression examined associations between anticholinergic use (measured during baseline [Visit 1] and average 7-year follow up [Visit 2]) with global cognition, episodic learning, memory, phonemic fluency, processing speed, executive functioning, and average 7-year change.

R

SUBMITTER: Posis AIB 

PROVIDER: S-EPMC9632492 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature