Dopamine versus norepinephrine as the first-line vasopressor in the treatment of cardiogenic shock.

ABSTRACT:

Background

Only a few observational studies using small patient samples and one subgroup analysis have compared norepinephrine and dopamine for the treatment of cardiogenic shock (CS). The objective of the present study was to investigate whether the use of norepinephrine was associated with improvements in clinical outcomes in CS patients compared to dopamine.

Methods

We retrospectively reviewed hospital medical records of patients who were admitted to cardiac intensive care unit from 2012 to 2018. We included 520 patients with CS in this analysis. The primary outcome was in-hospital mortality, and serial hemodynamic data were also assessed.

Results

As a first-line vasopressor, dopamine was used in 156 patients (30%) and norepinephrine in 364 patients (70%). Overall,

SUBMITTER: Na SJ 

PROVIDER: S-EPMC9632770 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature