New insights into antibody levels against SARS-CoV-2 for healthcare personnel vaccinated with tozinameran (Comirnaty)

ABSTRACT:

Aim

The aim of this study is to determine the levels of spike protein IgG and total antibodies in subjects vaccinated against SARS-CoV-2 (both infected and non-infected) and the titer evolution over time. In addition, we also addressed the performance of each of the included platforms in the study, as they are intended to measure antibody levels in naturally infected patients.

Materials and methods

An observational study including 288 volunteer healthcare professionals vaccinated against SARS-CoV-2 (Comirnaty™) at the Andújar Alto Guadalquivir Hospital. Serum samples were obtained in September 2020 and 14 and 90 days after administration of the second dose. The following in vitro methods were used: Elecsys Anti‐SARS‐CoV‐2 N and Elecsys Anti-SARS-CoV-2 S (Roche, Germany) a

SUBMITTER: Fernandez-Suarez A 

PROVIDER: S-EPMC9632819 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature