Histological regression of peritoneal metastases of recurrent tubo-ovarian cancer after systemic chemotherapy.

ABSTRACT:

Introduction

Post-treatment histological regression of peritoneal metastases (PM) is a new and potentially important predictor of oncological outcomes. Histology of PM from adnexal origin is usually evaluated by the Chemotherapy Response Score (CRS). The aim of this preliminary study was to quantify the response of PM of recurrent tubo-ovarian cancer (TOVC) after systemic chemotherapy by using the recently validated Peritoneal Regression Grading System (PRGS) and compare it with CRS. Correlation with per operative evaluation through Peritoneal Cancer Index (PCI) was performed.

Material and methods

Retrospective cohort study of all consecutive patients with recurrent PM from TOVC undergoing surgery after prior systemic chemotherapy from January 2015 to March 2019. Biop

SUBMITTER: Pache B 

PROVIDER: S-EPMC9632969 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature