Investigating sex differences in T regulatory cells from cisgender and transgender healthy individuals and patients with autoimmune inflammatory disease: a cross-sectional study.
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ABSTRACT:
SUBMITTER: Robinson GA
PROVIDER: S-EPMC9633330 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Publications
Investigating sex differences in T regulatory cells from cisgender and transgender healthy individuals and patients with autoimmune inflammatory disease: a cross-sectional study.
Robinson George A GA Peng Junjie J Peckham Hannah H Butler Gary G Pineda-Torra Ines I Ciurtin Coziana C Jury Elizabeth C EC
The Lancet. Rheumatology 20220831 10
<h4>Background</h4>Sexual dimorphisms, which vary depending on age group and pubertal status, have been described across both the innate and adaptive immune system. We explored the influence of sex hormones on immune phenotype in the context of adolescent health and autoimmunity.<h4>Methods</h4>In this cross-sectional study, healthy, post-pubertal cisgender individuals (aged 16-25 years); healthy, pre-pubertal cisgender individuals (aged 6-11 years); transgender individuals (aged 18-19 years) un ...[more]
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