Real-world evaluation of supportive care using an electronic health record text-mining tool: G-CSF use in breast cancer patients.

ABSTRACT:

Purpose

Chemotherapy-induced febrile neutropenia (FN) is a life-threatening and chemotherapy dose-limiting adverse event. FN can be prevented with granulocyte-colony stimulating factors (G-CSFs). Guidelines recommend primary G-CSF use for patients receiving either high (> 20%) FN risk (HR) chemotherapy, or intermediate (10-20%) FN risk (IR) chemotherapy if the overall risk with additional patient-related risk factors exceeds 20%. In this study, we applied an EHR text-mining tool for real-world G-CSF treatment evaluation in breast cancer patients.

Methods

Breast cancer patients receiving IR or HR chemotherapy treatments between January 2015 and February 2021 at LUMC, the Netherlands, were included. We retrospectively collected data from EHR with a text-mining tool and assesse

SUBMITTER: van Laar SA 

PROVIDER: S-EPMC9633501 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature