Antibiofilm properties of bioactive compounds from Actinomycetes against foodborne and fish pathogens.

ABSTRACT: In nature, bacteria can form biofilms, multi-layered structures that adhere microbial populations to solid surfaces by exopolysaccharides, proteins, and nucleic acids. In addition to causing foodborne infections, biofilms can be a major problem in aquaculture. Actinomycetes extracts have previously demonstrated antibiofilm activity against multiple foodborne and fish pathogens, and further characterization of these extracts is needed. In this study, we identified the chemical structures and antibiofilm properties of four extracts and determined the genetic similarity of the isolates to known Streptomyces isolates. We found that several extracts contained multiple antibiofilm compounds, and the antibiofilm activities of all extracts were most stable at pH 6. Furthermore, the antibiofilm inh

SUBMITTER: Miller T 

PROVIDER: S-EPMC9633603 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature