Ontology highlight
ABSTRACT:
SUBMITTER: Kopec M
PROVIDER: S-EPMC9633797 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
Kopeć M M Beton K K Jarczewska K K Abramczyk H H
Scientific reports 20221103 1
Raman spectroscopy and Raman imaging were used to identify the biochemical and structural features of human cancer lung cells (CCL-185) and the cancer cells supplemented with glucose and deuterated glucose at normal and hyperglycemia conditions. We found that isotope substitution of glucose by deuterated glucose allows to separate de novo lipid synthesis from exogenous uptake of lipids obtained from the diet. We demonstrated that glucose is largely utilized for de novo lipid synthesis. Our resul ...[more]