Effects of Empagliflozin on Diuretics Reduction in Outpatient Heart Failure Patients.

ABSTRACT:

Background and objectives

Inhibitors of sodium-glucose cotransporter 2 (SGLT2i) reduce the risk of hospitalization for heart failure (HF). We aimed to examine the effect of empagliflozin on change of diuretics dose in outpatient HF patients.

Methods

We retrospectively reviewed the medical records of 612 patients who were treated using both empagliflozin and diuretics. We excluded patients who did not meet the criteria for HF. Dose and duration of empagliflozin and diuretics were measured.

Results

Of 612 patients, a total of 251 was analyzed and followed for a mean 430.0±175.4 days. The mean age was 69.3, 51.8% were female, and 93.2% had type 2 diabetes. The distribution of initial diuretics type when starting empagliflozin showed that furosemide comprised 24.7%, spiro

SUBMITTER: Kim SJ 

PROVIDER: S-EPMC9634028 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature