Prognostic influence of an early time to chemotherapy following primary cytoreductive surgery for advanced epithelial ovarian cancer.

ABSTRACT:

Objective

The current investigation analyzes the prognostic role of the time to chemotherapy (TTC) interval following primary cytoreductive surgery for patients with advanced epithelial ovarian cancer.

Methods

Characteristics and outcome data for 509 consecutive patients with stage IIIB-IVB ovarian, fallopian tube, and peritoneal cancer who had primary cytoreductive surgery between January 2000 and December 2019 are utilized. A univariate Cox regression determined the association of categorical variables with progression-free survival (PFS) and overall survival (OS). Significant variables (p≤0.05) on univariate analysis were applied to Cox proportional hazard regression.

Results

The median TTC was 19 days and overall follow-up was 62.2 months. The PFS and OS were 25.5

SUBMITTER: Eisenkop SM 

PROVIDER: S-EPMC9634102 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature