Stress-Induced Changes in Effective Connectivity During Regulation of the Emotional Response to Threat.

ABSTRACT: Background: Stress-related disruption of emotion regulation appears to involve the prefrontal cortex (PFC) and amygdala. However, the interactions between brain regions that mediate stress-induced changes in emotion regulation remain unclear. The present study builds upon prior work that assessed stress-induced changes in the neurobehavioral response to threat by investigating effective connectivity between these brain regions. Methods: Participants completed the Montreal Imaging Stress Task followed by a Pavlovian fear conditioning procedure during functional magnetic resonance imaging. Stress ratings and psychophysiological responses were used to assess stress reactivity. Effective connectivity during fear conditioning was identified using multivariate autoreg

SUBMITTER: Goodman AM 

PROVIDER: S-EPMC9634990 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature