[Improved quality of stored packed red blood cells by mechanical rinsing].

ABSTRACT:

Background

The transfusion of packed red blood cells (PRBC) is associated with various side effects, including storage damage to PRBCs. The cells change their structure, releasing potassium as well as lactate. Mechanical rinsing, available in many hospitals, is able to remove toxic substances and possibly minimizes the negative side effects of transfusion.

Objective

The primary aim of our study was to improve the quality of PRBCs before transfusion. The effects of different washing solutions on PRBC quality were analyzed.

Material and methods

This in vitro study compares 30 mechanically washed PRBCs. They were either processed with standard normal saline 0.9% (n = 15, N group) or a hemofiltration solution containing 4 mmol/l potassium (n = 15, HF group) by a mechanica

SUBMITTER: Munch F 

PROVIDER: S-EPMC9636120 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature