Changes in pathogens of neonatal bacterial meningitis over the past 12 years: a single-center retrospective study

ABSTRACT:

Background

Bacterial meningitis is a serious central nervous system infection associated with high morbidity and mortality during the neonatal period, while the pathogen distribution was rarely reported on a large scale in China. This study aimed to investigate the distribution and change trends of neonatal bacterial meningitis pathogens in Children’s Hospital of Fudan University over the past 12 years.

Methods

This retrospective study included all cases diagnosed with neonatal bacterial meningitis and admitted to our hospital from 2009 to 2020.

Results

Totally 231 cases were enrolled, including 128 (55.4%) for male, 72 (31.2%) for premature infants, 48 (20.8%) for early-onset meningitis. The most common pathogens were Escherichia coli (E. coli) (39.0%) and Group

SUBMITTER: Zhai Q 

PROVIDER: S-EPMC9636462 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature