The g3mclass is a practical software for multiclass classification on biomarkers.

ABSTRACT: The analytes qualified as biomarkers are potent tools to diagnose various diseases, monitor therapy responses, and design therapeutic interventions. The early assessment of the diverseness of human disease is essential for the speedy and cost-efficient implementation of personalized medicine. We developed g3mclass, the Gaussian mixture modeling software for molecular assay data classification. This software automates the validated multiclass classifier applicable to single analyte tests and multiplexing assays. The g3mclass achieves automation using the original semi-constrained expectation-maximization (EM) algorithm that allows inference from the test, control, and query data that human experts cannot interpret. In this study, we used real-world clinical data and gene expression datasets

SUBMITTER: Guvakova MA 

PROVIDER: S-EPMC9637185 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature