Short-term safety of COVID-19 mRNA vaccines with respect to all-cause mortality in the older population in Norway.

ABSTRACT:

Background

There have been concerns about COVID-19 vaccination safety among frail older individuals. We investigated the relationship between COVID-19 mRNA vaccination and mortality among individuals aged ≥ 70 years and whether mortality varies across four groups of health services used.

Methods

In this nationwide cohort study, we included 688,152 individuals aged ≥ 70 years at the start of the Norwegian vaccination campaign (December 27, 2020). We collected individual-level data from theNorwegian Emergency Preparedness Register for COVID-19. Vaccinated and unvaccinated individuals were matched (1:1 ratio) on the date of vaccination based on sociodemographic and clinical characteristics. The main outcome was all-cause mortality during 21 days after first dose of COVID-19 mRN

SUBMITTER: Lopez-Doriga Ruiz P 

PROVIDER: S-EPMC9637531 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature