Development and validation of a population-based prognostic nomogram for primary colorectal lymphoma patients.

ABSTRACT:

Background

Primary colorectal lymphoma (PCL) is a relatively rare cancer type, constituting 15%-20% of primary gastrointestinal lymphoma and <1% of all colorectal malignancies. Given its low incidence, standard guidelines for case management are not available. This large population-based study aims to construct a nomogram to predict survival outcomes and to help tailor individualised treatment decisions in patients with PCL.

Methods

A retrospective cohort study of patients with PCL was developed using data registered in the Surveillance, Epidemiology, and End Results (SEER) database between 1990 and 2015. The prognostic nomogram was constructed using R software after univariate and multivariate Cox regression analyses. Cox regression models were assessed using the proportion

SUBMITTER: Chen Q 

PROVIDER: S-EPMC9638023 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature