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Pharmacological interventions on smoking cessation: A systematic review and network meta-analysis.


ABSTRACT: Objective: A network meta-analysis based on randomized controlled trials was conducted to investigate the effects of pharmacological interventions on smoking cessation. Methods: English databases were searched to obtain randomized controlled trials reporting the effect of pharmacological interventions on smoking cessation. The risk of bias for the included trials was assessed using Cochrane Handbook tool. Stata 15.1 software was used to perform network meta-analysis, and GRADE approach was used to assess the evidence credibility on the effects of different interventions on smoking cessation. Results: A total of 159 studies involving 60,285 smokers were included in the network meta-analysis. The analysis involved 15 interventions and which yielded 105 pairs of compariso

SUBMITTER: Shang X 

PROVIDER: S-EPMC9638092 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature