Gut transcriptome reveals differential gene expression and enriched pathways linked to immune activation in response to weaning in pigs.

ABSTRACT: Weaning represents one of the most critical periods in pig production associated with increase in disease risk, reduction in performance and economic loss. Physiological changes faced by piglets during the weaning period have been well characterised, however little is currently known about the underlying molecular pathways involved in these processes. As pig meat remains one of the most consumed sources of protein worldwide, understanding how these changes are mediated is critical to improve pig production and consequently sustainable food production globally. In this study, we evaluated the effect of weaning on transcriptomic changes in the colon of healthy piglets over time using an RNA-sequencing approach. The findings revealed a complex and coordinated response to weaning with the majo

SUBMITTER: Le Bon M 

PROVIDER: S-EPMC9638111 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature