Effect of garlic extract on weight loss and gut microbiota composition in obese women: A double-blind randomized controlled trial.

ABSTRACT:

Objective

From a nutritional perspective, garlic extract could be a prebiotic product, which is useful for obese subjects, and one of its health-promoting underlying mechanisms is modulating gut microbiota composition. In this randomized double-blind clinical trial, the goal was to determine the effect of Allium (garlic extract) on anthropometric indices and gut microbiota composition in obese women following a low-calorie diet.

Materials and methods

Forty-three obese women were randomly divided into garlic extract (400 mg Allium sativum powder containing 1,100 mcg allicin/tablet) or placebo groups. During the 2 months of the study, each participant took two tablets per day. At the beginning and at the end of the clinical trial, anthropometric measurements were

SUBMITTER: Ettehad-Marvasti F 

PROVIDER: S-EPMC9638143 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature