Genomic Medicine in Periodontal Disease: Old Issue, New Insights.

ABSTRACT: Genetic variability is the main cause of phenotypic variation. Some variants may be associated with several diseases and can be used as risk biomarkers, identifying animals with higher susceptibility to develop the pathology. Genomic medicine uses this genetic information for risk calculation, clinical diagnosis and prognosis, allowing the implementation of more effective preventive strategies and/or personalized therapies. Periodontal disease (PD) is the inflammation of the periodontium induced mainly by bacterial plaque and is the leading cause of tooth loss. Microbial factors are responsible for the PD initiation; however, several studies support the genetic influence on the PD progression. The main purpose of the present publication is to highlight the main steps involved in the genomi

SUBMITTER: Goncalves-Anjo N 

PROVIDER: S-EPMC9638704 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature