Characterizing Tumor Thrombus Arising from Non-Clear Cell Renal Cell Carcinoma.

ABSTRACT:

Background

Renal cell carcinoma (RCC) can exhibit a unique vascular tropism that enables tumor thrombus extension into the inferior vena cava (IVC). While most RCC subtypes that form tumor thrombi are of clear cell (cc) histology, non-clear cell (ncc) subtypes can also exhibit this unique growth pattern.

Objective

To characterize clinicopathologic differences and survival outcomes among patients with IVC tumor thrombus arising from ccRCC versus nccRCC.

Design setting and participants

Patients diagnosed with IVC tumor thrombus secondary to RCC in our institutional experience from 2003 to 2021 were identified.

Outcome measurements and statistical analysis

Clinicopathologic characteristics were compared by histology. Perioperative and oncologic outcomes including

SUBMITTER: Rabinowitz MJ 

PROVIDER: S-EPMC9638762 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature