Association of physical activity and air pollution exposure with the risk of type 2 diabetes: a large population-based prospective cohort study

ABSTRACT:

Background

The interplay between physical activity (PA) and air pollution in relation to type 2 diabetes (T2D) remains largely unknown. Based on a large population-based cohort study, this study aimed to examine whether the benefits of PA with respect to the risk of T2D are moderated by exposure to air pollution.

Methods

UK Biobank participants (n = 359,153) without diabetes at baseline were included. Information on PA was obtained using the International Physical Activity Questionnaire short form. Exposure to air pollution, including PM2.5, PMcoarse (PM2.5−10), PM10, and NO2, was estimated from land use regression models. Cox regression models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (95% CIs).

Results

During a median of 8.9 yea

SUBMITTER: Li Z 

PROVIDER: S-EPMC9639290 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature