Association between decreased ipsilateral renal function and aggressive behavior in renal cell carcinoma.

ABSTRACT:

Background

To assess prognostic value of pre-operative ipsilateral split renal function (SRF) on disease-free survival (DFS) and its association with aggressive pathological features in renal cell carcinoma (RCC) patients.  METHODS: We examined patients registered in SNUG-RCC-Nx who underwent partial or radical nephrectomy at Seoul National University Hospital between January 1, 2010 and December 31, 2020. Patients with the following criteria were excluded from the study. 1) non-kidney origin cancer or benign renal tumor, 2) no pre-operative Tc 99 m-DTPA renal scan, 3) single kidney status or previous partial or radical nephrectomy, and 4) bilateral renal mass. Finally, 1,078 patients were included.

Results

Among 1,078 patients, 899 (83.4%) showed maintained ipsilateral SRF

SUBMITTER: Han JH 

PROVIDER: S-EPMC9639309 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature