A novel diagnostic model for differentiation of lung metastasis from primary lung cancer in patients with colorectal cancer.

ABSTRACT:

Objective

This study aimed to evaluate the ¹⁸F-FDG PET/CT in differentiating lung metastasis(LM) from primary lung cancer(LC) in patients with colorectal cancer (CRC).

Methods

A total of 120 CRC patients (80 male, 40 female) who underwent ¹⁸F-FDG PET/CT were included. The diagnosis of primary lung cancer or lung metastasis was based on histopathology The patients were divided into a training cohort and a validation cohort randomized 1:1. Independent risk factors were extracted through the clinical information and ¹⁸F-FDG PET/CT imaging characteristics of patients in the validation cohort, and then a diagnostic model was constructed and a nomograms was made. ROC curve, calibration curve, cutoff, sensitivity, specificity, and accuracy were used

SUBMITTER: Guo R 

PROVIDER: S-EPMC9639374 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature