Genetics of COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome: a systematic review.

ABSTRACT: COVID-19 and ME/CFS present with some similar symptoms, especially physical and mental fatigue. In order to understand the basis of these similarities and the possibility of underlying common genetic components, we performed a systematic review of all published genetic association and cohort studies regarding COVID-19 and ME/CFS and extracted the genes along with the genetic variants investigated. We then performed gene ontology and pathway analysis of those genes that gave significant results in the individual studies to yield functional annotations of the studied genes using protein analysis through evolutionary relationships (PANTHER) VERSION 17.0 software. Finally, we identified the common genetic components of these two conditions. Seventy-one studies for COVID-19 and 26 studies for M

SUBMITTER: Tziastoudi M 

PROVIDER: S-EPMC9639636 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature