Effectiveness of non-invasive respiratory support strategies in patients with COVID-19: A systematic review and meta analysis.

ABSTRACT:

Background

BackgroundThe effectiveness of non-invasive respiratory strategies, namely CPAP and HFNO, in reducing the risk of mortality and tracheal intubation in patients with severe COVID-19 is not well established.

Methods

A thorough literature search was conducted across 3 electronic databases (Medline, EMBASE and Cochrane Central) from inception through July 2022. Randomized controlled trials (RCTs) and observational studies assessing the impact of CPAP or HFNO on clinical outcomes in patients infected with COVID-19 were considered for inclusion. End-points included all-cause mortality and risk of tracheal intubation. Evaluations were reported as risk ratios (RRs) with 95% confidence intervals (CI) and analysis was performed using a random effects model. I² in

SUBMITTER: Kumar V 

PROVIDER: S-EPMC9640384 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature