Impact of elevated body mass index on cumulative live birth rate and obstetric safety in women undergoing assisted reproductive technology.

ABSTRACT: This study evaluated the impact of elevated body mass index (BMI) on short- and long-term outcomes of in-vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) treatments. A total of 7229 patients undergoing IVF/ICSI fresh cycles and subsequent frozen embryo transfer cycles from 2014 to 2020 were divided into normal (18.5-24.9 kg/m²) and high BMI (≥ 25 kg/m²) groups. Ovarian response, pregnancy outcomes, and safety of both mother and fetus were the main outcome measures. Furthermore, multivariate analysis was used to determine whether BMI was associated with cumulative live birth rate (CLBR). Results showed that for younger women (< 38 year), CLBR was significantly reduced in the high BMI group compared with the normal BMI control and was accompanied by few

SUBMITTER: Hu D 

PROVIDER: S-EPMC9640544 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature