Learned end-to-end high-resolution lensless fiber imaging towards real-time cancer diagnosis.

ABSTRACT: Recent advances in label-free histology promise a new era for real-time diagnosis in neurosurgery. Deep learning using autofluorescence is promising for tumor classification without histochemical staining process. The high image resolution and minimally invasive diagnostics with negligible tissue damage is of great importance. The state of the art is raster scanning endoscopes, but the distal lens optics limits the size. Lensless fiber bundle endoscopy offers both small diameters of a few 100 microns and the suitability as single-use probes, which is beneficial in sterilization. The problem is the inherent honeycomb artifacts of coherent fiber bundles (CFB). For the first time, we demonstrate an end-to-end lensless fiber imaging with exploiting the near-field. The framework includes resolu

SUBMITTER: Wu J 

PROVIDER: S-EPMC9640670 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature