Investigating the effects of low intensity visible light on human keratinocytes using a customized LED exposure system.

ABSTRACT: Photobiomodulation (PBM) refers to the use of light to modulate cellular processes, and has demonstrated utility in improving wound healing outcomes, and reducing pain and inflammation. Despite the potential benefits of PBM, the precise molecular mechanisms through which it influences cell behavior are not yet well understood. Inconsistent reporting of key light parameters has created uncertainty around optimal exposure profiles. In addition, very low intensities of light, < 0.1 J/cm², have not been thoroughly examined for their use in PBM. Here, we present a custom-made compact, and modular LED-based exposure system for studying the effects of very low-intensity visible light (cell proliferation, migration, ROS production, and mitochondrial membrane potential) of three differen

SUBMITTER: Sutterby E 

PROVIDER: S-EPMC9640685 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature