FDG PET and CT radiomics in diagnosis and prognosis of non-small-cell lung cancer.

ABSTRACT:

Background

¹⁸F-FDG PET and CT radiomics has been the object of a wide research for over 20 years but its contribution to clinical practice remains not yet well established. We have investigated its impact versus that of only histo-clinical data, for the routine management of non-small-cell lung cancer (NSCLC).

Methods

Our patients were retrospectively considered. They all had a FDG PET-CT and immuno-histo-chemistry (IHC) to assess PD-L1 expression at the beginning of the disease. A prognosis univariate and multivariate Cox survival analyses was performed for overall survival (OS) and progression free survival (PFS) prediction, including a training/testing procedure. Two sets of 47 PET and 47 CT radiomics features (RFs) were extracted. Difference between RFs accord

SUBMITTER: Hannequin P 

PROVIDER: S-EPMC9641045 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature