Surgical treatment of intermediate to high grade thymic neuroendocrine neoplasms: case series of five patients and literature review

ABSTRACT:

Background

Thymic neuroendocrine neoplasms (Th-NENs) are extremely rare. Th-NENs are divided into four pathological subtypes: typical carcinoid (TC), atypical carcinoid (AC), large cell neuroendocrine carcinoma (LCNEC), and small cell carcinoma (SCC). The latter three subtypes are highly aggressive with poor prognosis. There are limited reports on the optimal surgical strategies for Th-NENs. This study aims to report a case series of Th-NENs after surgical treatment and review the literatures.

Methods

We report a case series of five patients diagnosed with Th-NENs and summarize their clinical characteristics. Literatures related to surgical treatment of Th-NENs were reviewed.

Results

There were three males and two females, and mean age was 53.6 years. No myasthen

SUBMITTER:  

PROVIDER: S-EPMC9641081 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature