Cuproptosis associated genes affect prognosis and tumor microenvironment infiltration characterization in lung adenocarcinoma.

ABSTRACT: Cuproptosis, a newly discovered mechanism of programmed cell death, is important for detailing the metabolic aspects of cancer progression and thereby guiding cancer therapy. An exciting era of translational medicine has led to the rapid development of countless immunotherapeutic strategies. The existing successful cancer immunotherapies have sparked new hope for patients with solid and hematologic malignancies. Hence, it is important to characterize the link between the cuproptosis process and the immunity status in the tumor microenvironment (TME) in Lung Adenocarcinoma (LUAD), which may be able to predict patient's prognosis. In this study, we systematically assessed 10 cuproptosis-associated genes (CAGs) and comprehensively characterized the relationship between cuproptosis and the mol

SUBMITTER: Sun X 

PROVIDER: S-EPMC9641400 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature