Gamma-band entrainment abnormalities in schizophrenia: Modality-specific or cortex-wide impairment?

ABSTRACT: A growing body of literature suggests that cognitive impairment in people with schizophrenia (PSZ) results from disrupted cortical excitatory/inhibitory (E-I) balance, which may be linked to gamma entrainment and can be measured noninvasively using electroencephalography (EEG). However, it is not yet known the degree to which these entrainment abnormalities covary within subjects across sensory modalities. Furthermore, the degree to which cross-modal gamma entrainment reflects variation in biological processes associated with cognitive performance remains unclear. We used EEG to measure entrainment to repetitive auditory and visual stimulation at beta (20 Hz) and gamma (30 and 40 Hz) frequencies in PSZ (n = 78) and healthy control subjects (HCS; n = 80). Three indices were measured for eac

SUBMITTER: Erickson MA 

PROVIDER: S-EPMC9641553 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature