A functional magnetic resonance imaging study of frontal networks in obsessive-compulsive disorder during cognitive reappraisal.

ABSTRACT:

Background

Patients with obsessive-compulsive disorder (OCD) present difficulties in the cognitive regulation of emotions, possibly because of inefficient recruitment of distributed patterns of frontal cortex regions. The aim of the present study is to characterize the brain networks, and their dysfunctions, related to emotion regulation alterations observed during cognitive reappraisal in OCD.

Methods

Adult patients with OCD (n = 31) and healthy controls (HC; n = 30) were compared during performance of a functional magnetic resonance imaging cognitive reappraisal protocol. We used a free independent component analysis approach to analyze network-level alterations during emotional experience and regulation. Correlations with behavioral scores were also explored

SUBMITTER: De la Pena-Arteaga V 

PROVIDER: S-EPMC9641649 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature