Preserved C-peptide secretion is associated with higher time in range (TIR) on intermittently scanned continuous glucose monitoring in Chinese adults with type 1 diabetes.

ABSTRACT:

Objective

To explore the relationship between C-peptide secretion and time in range (TIR) in adult patients with type 1 diabetes.

Methods

From December 2018 to December 2020, 76 type 1 diabetes participants were enrolled from the Department of Endocrinology and Metabolism of Peking University People's Hospital. All participants wore intermittently scanned continuous glucose monitoring (isCGM), and insulin dosage was adjusted according to standardized clinical procedures. Subjects were divided into low C-peptide group (<10 pmol/L) and preserved C-peptide group (10-200 pmol/L) based on fasting serum C-peptide levels. Differences of TIR, metrics related to glucose variability and hypoglycemic events were compared.

Results

A total of 94,846 isCGM values obtained from 39 m

SUBMITTER: Liu W 

PROVIDER: S-EPMC9641764 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature