NT-ProBNP and mortality across the spectrum of glucose tolerance in the general US population.

ABSTRACT:

Background

Even though hyperglycemia is a well-known cardiovascular risk factor, the absolute risk of cardiovascular events varies to a great extent within each glycemic category. The aim of this study is to evaluate whether N-terminal pro-B natriuretic peptide (NT-ProBNP) could help identify subjects at higher cardiovascular risk, independently of blood glucose levels.

Methods

Serum NT-ProBNP levels were measured in 5502 people aged 45-79 years without heart failure from the general population (3380 with normoglycemia, 1125 with pre-diabetes and 997 with diabetes) that participated in the 1999-2004 cycles of the National Health and Nutrition Examination Survey. We applied Cox and Fine Gray models adjusted for cardiovascular risk factors to evaluate the association between N

SUBMITTER: Ciardullo S 

PROVIDER: S-EPMC9641859 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature