Distribution of age, sex, race, and ethnicity in COVID-19 clinical drug trials in the United States: A review.

ABSTRACT:

Background

COVID-19 quickly overwhelmed the world, but disproportionately affects certain communities, particularly minority groups. Despite overrepresentation among COVID-19 cases and death, minority groups were underrepresented in some of the early COVID-19 clinical trials.

Objective

To assess and compare the demographic characteristics of COVID-19 clinical trial participants to national COVID-19 data.

Methods

PubMed was searched from December 1, 2019 to November 24, 2020, for randomized controlled trials evaluating a pharmacologic treatment for COVID-19 patients from one or more U.S. sites written in the English language following the PRISMA checklist. Descriptive statistics were calculated to characterize patient demographics enrolled in the included clinical tria

SUBMITTER: Chastain DB 

PROVIDER: S-EPMC9642036 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature