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The regulation of antiviral activity of interferon epsilon.


ABSTRACT: Interferon epsilon (IFN-ε) is a type I IFN. Some biological properties has been identified in many species, such as antiproliferative, anti-tumor, and antiviral effects, of IFN-ε, which are much weaker than those of IFN-α, have also been revealed. It has been shown to play a role in mucosal immunity and bacterial infection and in the prevention of certain sexually transmitted diseases, such as human immunodeficiency virus (HIV). This paper reviews the known activity of IFN-ε, particularly in some viruses. In general, this review provides a better understanding of effective IFN-ε treatment in the future.

SUBMITTER: Zhao FR 

PROVIDER: S-EPMC9642105 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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The regulation of antiviral activity of interferon epsilon.

Zhao Fu-Rong FR   Wang Wei W   Zheng Qin Q   Zhang Yan-Ge YG   Chen Jianming J  

Frontiers in microbiology 20221025


Interferon epsilon (IFN-ε) is a type I IFN. Some biological properties has been identified in many species, such as antiproliferative, anti-tumor, and antiviral effects, of IFN-ε, which are much weaker than those of IFN-α, have also been revealed. It has been shown to play a role in mucosal immunity and bacterial infection and in the prevention of certain sexually transmitted diseases, such as human immunodeficiency virus (HIV). This paper reviews the known activity of IFN-ε, particularly in som  ...[more]

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