Bayesian analysis of a systematic review of early versus late tracheostomy in ICU patients.

ABSTRACT:

Background

A recent systematic review and meta-analysis of RCTs of early vs late tracheostomy in mechanically ventilated patients suggest that early tracheostomy reduces the duration of ICU stay and mechanical ventilation, but does not reduce short-term mortality or ventilator-associated pneumonia (VAP). Meta-analysis of randomised trials is typically performed using a frequentist approach, and although reporting confidence intervals, interpretation is usually based on statistical significance. To provide a robust basis for clinical decision-making, we completed the search used from the previous review and analysed the data using Bayesian methods to estimate posterior probabilities of the effect of early tracheostomy on clinical outcomes.

Methods

The search was completed for

SUBMITTER: Quinn L 

PROVIDER: S-EPMC9642836 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature